Table 4.
Univariate and multivariable logistic analysis of clinical, MR and pathological features for predicting TNBC subtypes in the training set.
| Variable | No. | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|---|
| OR (95%CI) | P value | OR (95%CI) | P value | |||
| Clinicopathologic factors | ||||||
| Age (years) | 1.003 (0.967,1.041) | 0.853 | ||||
| Axillary lymph node | 0.336 (0.102,1.112) | 0.074 | ||||
| Negative | 55 | Ref | ||||
| Positive | 33 | |||||
| Menopausal status | 1.242 (0.454,3.398) | 0.672 | ||||
| Premenopausal | 52 | Ref | ||||
| Postmenopausal | 36 | |||||
| Location | 1.429 (0.525,3.886) | 0.485 | ||||
| L | 50 | Ref | ||||
| R | 38 | |||||
| Pathological grade | 3.883 (1.359,11.096) | 0.019 | 1.776 (0.444, 7.098) | 0.417 | ||
| 2 | 53 | Ref | ||||
| 3 | 35 | |||||
| DCIS present | 0.223 (0.027,1.818) | 0.161 | ||||
| No | 74 | Ref | ||||
| yes | 14 | |||||
| MR factors | ||||||
| Size (mm) | ||||||
| ≤20 | 20 | Ref | ||||
| >20and≤50 | 50 | 0.389 (0.062,2.438) | 0.313 | |||
| >50 | 18 | 1.361 (0.382,4.852) | 0.635 | |||
| T2WI | 0.415 (0.064,2.678) | 0.356 | ||||
| Hypo or isointense | 83 | Ref | ||||
| Hyperintense | 5 | |||||
| T1WI | 4.000 (0.901,17.753) | 0.068 | ||||
| Hypo or isointense | 80 | Ref | ||||
| Hyperintense | 8 | |||||
| Shape | 0.720 (0.249,2.080) | 0.544 | ||||
| Round/oval | 26 | Ref | ||||
| Irregular | 62 | |||||
| Lesion type | 0.059 (0.007,0.468) | 0.007 | 0.009 (0,0.147) | 0.001 | ||
| Mass | 55 | Ref | ||||
| Nonmass & both | 33 | |||||
| Internal enhancement pattern | 3.395 (1.209,9.535) | 0.020 | 37.197 (4.210,328.681) | 0.001 | ||
| Heterogeneous | 59 | Ref | ||||
| Rim enhancement | 29 | |||||
DCIS, ductal carcinoma in situ; TNBC, triple-negative breast cancer. P values ≤ 0.05 were considered statistically significant.
Bold means P values ≤0.05 were considered statistically significant.