Table 1.
Baseline characteristics of the intention-to-treat population, stratified by usual care group and prehabilitation
| Usual care (n = 128) | Prehabilitation (n = 123) | Total (n = 251) | p-Value | |
|---|---|---|---|---|
| Patient characteristics | ||||
| Median age, years (IQR) | 72 (68–76) | 75 (71–80) | 73 (69–79) | 0.003 |
| Gender | 0.052 | |||
| Male | 75 (58.6%) | 57 (46.3%) | 132 (52.6%) | |
| Civil status | 0.259 | |||
| Partnership | 94 (73.4%) | 92 (74.8%) | 186 (74.1%) | |
| Single | 18 (14.1%) | 23 (18.7%) | 41 (16.3%) | |
| Widowed | 15 (11.7%) | 8 (6.5%) | 23 (9.2%) | |
| Missing | 1 (0.8%) | 0 (0%) | 1 (0.4%) | |
| BMI, kg/m2 | 0.319 | |||
| < 18.5 | 2 (1.6%) | 0 (0%) | 2 (0.8%) | |
| 18.5–25 | 48 (37.5%) | 45 (36.6%) | 93 (37.1%) | |
| 25–30 | 51 (39.8%) | 43 (35.0%) | 94 (37.5%) | |
| ≥ 30 | 27 (21.1%) | 35 (28.5%) | 62 (24.7%) | |
| Smoking | 0.496 | |||
| Never | 58 (45.3%) | 50 (40.7%) | 108 (43.0%) | |
| Former | 58 (45.3%) | 65 (52.8%) | 123 (49.0%) | |
| Current | 11 (8.6%) | 8 (6.5%) | 19 (7.6%) | |
| Missing | 1 (0.8%) | 0 (0%) | 1 (0.4%) | |
| Alcohol use | < 0.001 | |||
| Never | 49 (38.3%) | 60 (48.8%) | 109 (43.4%) | |
| < 1/week | 28 (21.9%) | 8 (6.5%) | 36 (14.3%) | |
| ≥ 1/week < 2/daily | 26 (20.3%) | 42 (34.1%) | 68 (27.1%) | |
| ≥ 2/daily | 23 (18.0%) | 13 (10.6%) | 36 (14.3%) | |
| Missing | 2 (1.6%) | 0 (0%) | 2 (0.8%) | |
| Charlson comorbidity index | 0.621 | |||
| 0 | 66 (51.6%) | 58 (47.2%) | 124 (49.4%) | |
| 1 | 26 (20.3%) | 32 (26.0%) | 58 (23.1%) | |
| 2 | 24 (18.8%) | 19 (15.4%) | 43 (17.1%) | |
| ≥ 3 | 12 (9.4%) | 14 (11.4%) | 26 (10.4%) | |
| Polypharmacy (≥ 5 drugs) | 0.154 | |||
| Yes | 51 (39.8%) | 60 (48.8%) | 111 (44.2%) | |
| ASA index | 0.171 | |||
| I | 10 (7.8%) | 6 (4.9%) | 16 (6.4%) | |
| II | 74 (57.8%) | 61 (49.6%) | 135 (53.8%) | |
| III | 40 (31.3%) | 54 (43.9%) | 94 (37.5%) | |
| IV | 4 (3.1%) | 2 (1.6%) | 6 (2.4%) | |
| MET score | 0.438 | |||
| < 3 | 2 (1.6%) | 3 (2.4%) | 5 (2.0%) | |
| 3–6 | 43 (33.6%) | 72 (58.5%) | 115 (45.8%) | |
| >3 | 40 (31.3%) | 47 (38.2%) | 87 (34.7%) | |
| Missing | 43 (33.6%) | 1 (0.8%) | 44 (17.5%) | |
| SNAQ score | 0.950 | |||
| ≥ 3 | 15 (11.7%) | 16 (13.0%) | 31 (12.4%) | |
| Missing | 27 (21.1%) | 13 (10.6%) | 40 (15.9%) | |
| Anemia at inclusion | 0.012 | |||
| Yes | 48 (37.5%) | 66 (53.7%) | 114 (45.4%) | |
| Missing | 1 (0.8%) | 0 (0%) | 1 (0.4%) | |
| Tumor characteristics | ||||
| Tumor localisation | 0.056 | |||
| Colon | 61 (47.7%) | 76 (61.8%) | 137 (54.6%) | |
| Sigmoid | 48 (37.5%) | 37 (30.1%) | 85 (33.9%) | |
| Rectum | 19 (14.8%) | 10 (8.1%) | 29 (11.6%) | |
| Tumor stage | 0.114 | |||
| I | 36 (28.1%) | 33 (26.8%) | 69 (27.5%) | |
| II | 57 (44.5%) | 42 (34.1%) | 99 (39.4%) | |
| III | 35 (27.3%) | 48 (39.0%) | 84 (33.1%) | |
| Stoma at inclusion | 0.165 | |||
| Yes | 2 (1.6%) | 6 (4.9%) | 8 (3.2%) |
ASA American Society of Anesthesiologists, MET score Metabolic Equivalent of Task score, SNAQ score Short Nutritional Assessment Questionnaire score