Skip to main content
. Author manuscript; available in PMC: 2022 Oct 5.
Published in final edited form as: Cell Rep. 2022 Sep 20;40(12):111400. doi: 10.1016/j.celrep.2022.111400

Figure 1. Overview of this study.

Figure 1.

We performed RNA-seq and ChIP-seq on left ventricle samples from 18 healthy donors. We identified reproducible enhancer predictions and gene expression patterns in healthy heart (top). Next, we identified global alterations in enhancer occupancy from 18 hearts with idiopathic dilated cardiomyopathy (DCM, center). Last, we compared adult healthy and disease states with five embryonic or fetal hearts and identified similarities in the enhancer landscapes of DCM and fetal heart (bottom).