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. 2022 Aug 17. Online ahead of print. doi: 10.1016/j.ajog.2022.08.017

Figure 1.

Figure 1

Monkeypox virus

A, Monkeypox virus on transmission electron microscopy, negative staining (bar=200 nm). B, cutaway line drawing of the monkeypox virus. Tecovirimat targets the VP37 protein and inhibits formation of the viral envelope (E). Cidofovir targets DNA polymerase within the viral nucleosome (N) but is teratogenic, unlike tecovirimat. Image credit: Panel A – Andrea Männel 2001/ RKI Robert Koch Institute; Panel B – Authors’ original illustration using Biorender.

CM, core membrane; E, envelope; LB, lateral body; N, nucleosome; OM, outer membrane; ST, surface tubules.

Dashraath. Monkeypox and pregnancy. Am J Obstet Gynecol 2022.