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. 2022 Sep 21;13:952262. doi: 10.3389/fimmu.2022.952262

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Copyright © 2022 Yigitbilek, Ozdogan, Abrol, Park, Hansen, Dasari, Stegall and Taner

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The top protein sets that are differentially expressed (P<0.01) in L-MSC versus non-L-MSC secretome. The secretome data was subjected to protein ontology analysis to investigate the correlations between the intergroup differences and the functional changes observed on the immunomodulatory roles of MSCs from different tissue sources. Protein sets are that are enriched in the secretome of non-L-MSC are demonstrated at the top, and those enriched in the secretome of L-MSC are demonstrated at the bottom.