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. 2022 Sep 21;12:890825. doi: 10.3389/fonc.2022.890825

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Signaling axis connecting the KSHV encoded oncogene vGPCR to the HO-1 promoter (Hmox-1) involves Gα12/13 and RhoA dependent Erk1/2 MAPK mediated activation of the transcription factor Nrf2.