Figure 4.

Correlation of the inflammatory response-related polygenic risk score (IRPRS) with the clinicopathological characteristics and three known biomarkers. The IRPRS in different (a) sex, (b) age, (c) serum α-fetoprotein (AFP) levels, (d) vascular invasion status, (e) Eastern Cooperative Oncology Group (ECOG) performance status, (f) Child-Pugh liver function levels, and (g) American Joint Committee on Cancer stages. (h) The prognostic value of IRPRS is observed in the subset of serum AFP-negative HCC. The IRPRS shows no association with (i) GPC3 and is positively related with (j) HSP70 and negatively related with (k) GLUL.