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. 2022 Sep 28;610(7930):161–172. doi: 10.1038/s41586-022-05192-0

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 2 — a, Chronically LCMV-infected mice (> day 40 post-infection) were left untreated or treated with muPD-L1, muPD-L1 + muFAP-IL2wt, and muPD-L1 + muFAP-IL2v for 2 weeks and then analyzed for expansion of CD8 T cells. b, Representative FACS plots for CD8⁺ T cells in PBMCs. c, Numbers of CD8⁺ T cells per 10⁶ PBMCs. d, Representative FACS plots for CD44 and PD-1 expressions on CD8⁺ T cells in PBMCs. e, Numbers of CD44⁺PD-1⁻ and CD44⁺PD-1⁺ CD8⁺ T cells per 10⁶ PBMCs. Results were pooled from 3-4 experiments with n = 2–5 mice per group in each experiment. Data are presented as geometric mean and 95% CI with p values. Statistical comparisons were performed using one-way ANOVA with Tukey’s multiple comparison test. Untx, untreated.

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