Extended Data Fig. 10. Developmental trajectories and timing of the endoderm and extraembryonic contribution to gut formation.
a. Velocity plots of epiblast, definitive endoderm, gut precursors and primitive streak for all time points analysed in the inDrops sequencing dataset. b. Latent time analysis of epiblast, definitive endoderm, gut precursors and primitive streak for all time points analysed in the inDrops sequencing dataset. c. Quantification of latent time analysis of epiblast, definitive endoderm, gut precursors and primitive streak for all time points analysed in the inDrops sequencing dataset. d–k. Expression of selected marker genes of the embryonic (d-j) and extraembryonic (k) endoderm contribution to the gut (tiny sci-RNA-seq dataset). l. UMAP showing time series of individual natural embryos and ETiX embryoids to combined UMAP in Fig. 5d