Table 2.

Progression of the current amplitude (mA) of the stimulation parameters, and ankle weights of the right leg from week 1 to week 45 following LPWS protocol in the trial

		Repetitions	1	2	3	4	5	6	7	8	9	10
Week 1
Pulse width: 200 ms	Set 1	Amp (mA)-set 1	160	160	160	160	160	165	165	165	165	165
Pulse interval: 400 ms	Set 2	Amp (mA)-set 2	170	170	170	170	170	175	175	175	175	175
Frequency: 1.66 Hz	Set 3	Amp (mA)-set 3	180	180	180	180	180	185	185	185	185	185
Ankle weights: 0 lbs	Set 4	Amp (mA)-set 4	190	190	190	190	190	195	195	195	195	195
Week 45
Pulse width: 35 ms	Set 1	Amp (mA)-set 1	200	172	148	163	165	166	169	182	200	173
Pulse interval: 400 ms	Set 2	Amp (mA)-set 2	191	183	173	180	179	200	170	185	187	187
Frequency: 25 Hz	Set 3	Amp (mA)-set 3	200	177	163	194	200	199	200	200	170	191
Ankle weights: 2 lbs	Set 4	Amp (mA)-set 4	200	173	177	173	196	200	195	178	200	200

The highlighted region represents the amplitude in week 45.

Note the amplitude of the current increased approximately by 19% in week 1 from set 1 to set 4, this reflects the increase in muscle fatigue of the denervated knee extensor muscle group during one training session. This fatigue pattern decreased to only 9% in week 45 (ie, last training bout) following 12 months of training in one of the participants.

LPWS, long pulse width stimulation.