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. 2022 Oct 5;12(10):e054229. doi: 10.1136/bmjopen-2021-054229

Table 4.

Estimated association of adherence and group allocation at follow-up (aLiFE and eLiFE, n=120)

Unstandardised B Coefficient SE Stnβ 95% CI P value
Primary outcome measures
LLFDI
 LLFDI disability frequency
  Baseline score 0.677 0.065 0.716 0.549 to 0.80 0.000
  Group allocation 0.872 0.553 0.105 −0.226 to 1.970 0.118
  Predicted adherence level 0.080 0.127 0.042 −0.173 to 0.333 0.533
 LLFDI disability limitation (/100)
  Baseline score 0.663 0.081 0.621 0.502 to 0.824 0.000
  Group allocation −0.487 1.968 −0.017 −4.390 to 3.417 0.805
  Predicted adherence level 0.663 0.081 0.621 0.346 to 2.393 0.009
 LLFDI function total components
  Baseline score 0.779 0.064 0.760 0.652 to 0.906 0.000
  Group allocation −1.354 1.260 −0.057 −3.854 to 1.146 0.285
  Predicted adherence level 0.797 0.344 0.144 0.114 to 1.480 0.023
 LLFDI UE
  Baseline score 0.624 0.074 0.623 0.478 to 0.771 0.000
  Group allocation −0.667 1.694 −0.027 −4.028 to 2.693 0.694
  Predicted adherence level 1.113 0.418 0.197 0.285 to 1.942 0.009
 LLFDI BLE
  Baseline score 0.632 0.076 0.631 0.481 to 0.784 0.000
  Group allocation −1.994 1.788 −0.072 −5.540 to 1.552 0.267
  Predicted adherence level 1.304 0.486 0.204 0.339 to 2.268 0.009
 LLFDI ALE
  Baseline score 0.868 0.066 0.780 0.736 to 0.999 0.000
  Group allocation −1.934 1.763 −0.057 −5.431 to 1.562 0.275
  Predicted adherence level 1.000 0.467 0.127 0.074 to 1.926 0.035
Behavioural complexity
 Complexity, mean
  Baseline score 0.178 0.076 0.235 0.028 to 0.329 0.021
  Group allocation −0.012 0.019 −0.063 −0.049 to 0.025 0.525
  Predicted adherence level 0.008 0.004 0.185 −0.001 to 0.017 0.068
 Complexity, median (IQR)
  Baseline score 0.209 0.076 0.270 0.057 to 0.360 0.008
  Group allocation −0.007 0.019 −0.035 −0.045 to 0.031 0.726
  Predicted adherence level 0.008 0.004 0.186 −0.045 to 0.017 0.063
Secondary outcome measures
Cognition, affect and well-being
 MOCA score
  Baseline score 0.590 0.090 0.558 0.411 to 0.769 0.000
  Group allocation 0.190 0.328 0.049 −0.461 to 0.842 0.563
  Predicted adherence level −0.023 0.077 −0.026 −0.176 to 0.129 0.762
 CES-D score
  Baseline score 0.426 0.087 0.444 0.253 to 0.598 0.000
  Group allocation −0.586 0.903 −0.048 −2.377 to 1.205 0.518
  Predicted adherence level −0.889 0.257 −0.313 −1.399 to −0.380 0.001
 Short Form 12
  Baseline score 0.500 0.102 0.467 0.297 to 0.703 0.000
  Group allocation −0.990 0.517 −0.158 −2.017 to 0.037 0.059
  Predicated adherence level 0.231 0.138 0.160 −0.042 to 0.505 0.097
Physical ability and mobility*
 Usual gait speed (7 m walk)
  Baseline score 0.621 0.057 0.717 0.507 to 0.735 0.000
  Group allocation 0.041 0.027 0.097 −0.012 to 0.095 0.128
  Predicted adherence level 0.014 0.007 0.141 0.001 to 0.027 0.036
 CBMS (/96)
  Baseline score 0.847 0.073 0.796 0.702 to 0.992 0.000
  Group allocation 1.039 1.599 0.038 −2.134 to 4.212 0.517
  Predicated adherence level 0.206 0.431 0.033 −0.648 to 1.061 0.633
 8-Level Balance test
  Baseline score 0.467 0.116 0.396 0.237 to 0.697 0.000
  Group allocation 0.254 0.213 0.111 −0.168 to 0.677 0.235
  Predicted adherence level 0.047 0.051 0.089 −0.053 to 0.147 0.356

Bold p<0.05

*Strength and balance deficits known to influence adherence.

ALE, advanced lower extremity; aLiFE, adapted Lifestyle-integrated Functional Exercise; BLE, basic lower extremity; CBMS, Community Balance and Mobility Scale; CES-D, Center for Epidemiological Studies Depression; eLiFE, enhanced Lifestyle-integrated Functional Exercise; LLFDI, Late-Life Function and Disability Index; MOCA, Montreal Cognitive Assessment; UE, upper extremity; VAS, Visual Analogue Scale.