Table 1.

Key inclusion and exclusion criteria

Key inclusion criteria	Key exclusion criteria
Can present a skin area located in face, neck or chest of ≥25 cm2 with 4–8 actinic keratosis lesions	Actinic keratosis lesions classified as Olsen grade 3 in target area
Actinic keratosis lesions in target area of severity grade 1 or 2 as defined by the Olsen clinical criteria for actinic keratosis	Atypical actinic keratosis lesions in the target area, including suspected squamous cell carcinoma and basal cell carcinoma
Have a suitable smartphone to complete the trial tasks (Android operating system: Android 8.1 or higher; iPhone with iOS 12.4 or higher), and able and willing to follow the trial procedures by using the Study App	Any dermatological condition in the target area that can be exacerbated by treatment or affect assessments
Women must either be of non-childbearing potential or must be using a highly effective method of contraception for the duration of the study	Received lesion-directed or field-directed therapy within 2 cm of the target skin area within 1 month prior to baseline visit, including topical drugs, destructive therapies or field ablation treatments