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. 2022 Oct 4;85:104302. doi: 10.1016/j.ebiom.2022.104302

Figure 4.

Figure 4

(a) CDO1 mRNA levels in VAT and SAT cell fractions. ***P<0.001 compared to SVF (Unpaired t-test). (b-c)CDO1 mRNA during adipocyte differentiation in a time course experiment in human preadipocytes (b) and in ACS52telo cells (c). **P<0.01 and ***P<0.005 compared to day 0 (Mann Whitney test). (d) Effects of CDO1 gene KD on CDO1, adipogenic (ADIPOQ, FABP4, FASN, PPARG, SLC2A4, CEBPA)-related, mitochondrial (PPARGC1A)-related and inflammatory (IL6, TNF)-related gene expression, and on taurine levels in culture medium in human preadipocytes at day 14 of adipocyte differentiation. *P<0.05, **P<0.01 and ***P<0.005 compared to shRNA_SRC (Mann Whitney test).