TABLE 2.
Key metabolite measures (VIP ≥1) that discriminate women diagnosed with GDM from women without GDM in partial least squares discriminatory analysis1
| Variable | Model 1 | Model 2 |
|---|---|---|
| Age | 6.4 ± 0.03 | 5.9 ± 0.03 |
| BMI | 5.4 ± 0.04 | 5.1 ± 0.02 |
| Ethnicity | — | 2.9 ± 0.02 |
| Parity | 2.4 ± 0.01 | 2.3 ± 0.01 |
| Smoking status | 1.9 ± 0.02 | 1.7 ± 0.01 |
| Multiple pregnancy | 1.5 ± 0.01 | 1.3 ± 0.009 |
| Lactate | 1.5 ± 0.01 | 1.2 ± 0.008 |
| VLDL_D | 1.3 ± 0.01 | 1.3 ± 0.01 |
| Total fatty acids | 1.2 ± 0.01 | 1.5 ± 0.01 |
| Total MUFA | 1.2 ± 0.001 | 1.2 ± 0.008 |
| 18:2 linoleic acid | 1.1 ± 0.01 | 1.1 ± 0.004 |
| Total SFA | 1.1 ± 0.01 | 1.2 ± 0.007 |
| Esterified cholesterol | — | 1.0 ± 0.008 |
1
Variable of importance in projection (VIP) scores (mean ± SE) across 20 partial least squares discriminatory analysis iterations discriminating between women with GDM (n = 414) and women without GDM (n = 414). Model 1: Includes all metabolite measures plus BMI (continuous), maternal age (years), smoking status, parity, and multiple pregnancy status. Model 2: Model 1 + ethnicity. GDM, gestational diabetes mellitus; VLDL_D, mean diameter of VLDL.