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. 2022 Oct 5;158(12):1357–1366. doi: 10.1001/jamadermatol.2022.3917

Figure 4. Association of Apremilast With Protein Phosphorylation on Immunohistochemistry.

Figure 4.

A-B, Decrease in phosphorylated signal transducers and activators of transcription 1 (pSTAT1) immunostaining on a frozen section of patient 2 skin biopsies before and 3 months after apremilast (original magnification ×200). C-D, Paired analysis change in pSTAT1 percent positive cells and H score at baseline and 3 months after apremilast. E-F, Decrease in pSTAT3 immunostaining on frozen section from patient 2 skin biopsies before and 3 months after apremilast (original magnification ×200). G-H, Paired analysis change in pSTAT3 percent positive cells and H score at baseline and 3 months after apremilast.