Table 1.
Clinical and Laboratory Characteristics of Patients With Clonal Cytopenia of Undetermined Significance
| Characteristic or Marker | Patients With CCUS (n = 80) |
|---|---|
| Age, median (range), y | 72 (19-92) |
| Sex, No. (%) | |
| F | 21 (26) |
| M | 59 (74) |
| Splenomegaly, No. (%) | |
| No | 66 (83) |
| Yes | 14 (18) |
| Prior chemotherapy or RT, No. (%) | |
| No | 70 (88) |
| Yes | 10 (13) |
| ANC, median (range), ×109/L | 2.0 (0-40) |
| ALC, median (range), ×109/L | 1.26 (0.16-40) |
| WBC, median (range), ×109/L | 4.0 (0.3-23) |
| Hemoglobin, median (range), g/dL | 10.5 (6.8-14.9) |
| Platelet count, median (range), ×109/L | 126 (7-595) |
| High LDH (>222 U/L), No. (%) | |
| No | 23 (50) |
| Yes | 23 (50) |
| High ferritin (>336 µg/L), No. (%) | |
| No | 31 (39) |
| Yes | 21 (26) |
| Loss of Y chromosome, No. (%) | |
| No | 76 (95) |
| Yes | 4 (5) |
| del(20)(q11.q13.1), No. (%) | |
| No | 77 (96) |
| Yes | 3 (4) |
| Loss of X chromosome, No. (%) | |
| No | 78 (97) |
| Yes | 2 (3) |
ALC, absolute lymphocyte count; ANC, absolute neutrophil count; CCUS, clonal cytopenia of undetermined significance; LDH, lactate dehydrogenase; RT, radiation therapy.