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The 10 Most Common Genes Mutated in the Clonal Cytopenia of Undetermined Significance Cohort
| Mutation | VAF Range, % | Frequency of Mutation in Patients With CCUS, No. (%) (n = 80) |
|---|---|---|
| TET2 | 8-77 | 20 (25.0) |
| SRSF2 | 14-52 | 16 (20.0) |
| ASXL1 | 9-46 | 15 (18.75) |
| U2AF1 | 9-43 | 12 (15.0) |
| SF3B1 | 6-45 | 7 (8.75) |
| DNMT3a | 7-43 | 6 (7.5) |
| ZRSR2 | 57-88 | 6 (7.5) |
| IDH1 | 12-44 | 5 (6.25) |
| TP53 | 13-48 | 5 (6.25) |
| RUNX1 | 13-50 | 5 (6.25) |
CCUS, clonal cytopenia of undetermined significance; VAF, variant allele frequency.
