Table 3.
Zarit Burden score as a function of patient/caregiver characteristics
| Factors | N | Estimated Marginal Mean (SE)† | Beta† | 95% CI† | p † |
| Patient characteristics | |||||
| Sex | |||||
| female* | 648 | 52.1 (0.7) | – | ||
| male | 417 | 52.2 (0.9) | 0.09 | (–2.45 to 2.64) | 0.94 |
| Age categories | |||||
| 40–59* | 25 | 51.0 (3.0) | – | ||
| 60–69 | 80 | 51.9 (1.8) | 0.98 | (–5.62 to 7.59) | 0.77 |
| 70–79 | 321 | 52.5 (0.9) | 1.54 | (–4.65 to 7.72) | 0.63 |
| 80–89 | 546 | 52.4 (0.7) | 1.40 | (–4.75 to 7.54) | 0.66 |
| 90+ | 93 | 50.5 (1.6) | –0.49 | (–7.29 to 6.30) | 0.89 |
| Education | |||||
| primary education or less* | 424 | 52.0 (0.8) | – | ||
| secondary education or more | 641 | 52.3 (0.6) | 0.35 | (–1.64 to 2.34) | 0.73 |
| NPI profiles | |||||
| class 1 Affective | 387 | 50.6 (0.7) | 0.76 | (–1.28 to 2.81) | 0.46 |
| class 2 High behavioral dist. | 35 | 64.9 (2.5) | 14.99 | (9.90 to 20.09) | <0.01‡ |
| class 3 Negative affect | 110 | 54.9 (1.4) | 5.03 | (1.94 to 8.11) | <0.01‡ |
| class 4 Affective/deliriant | 122 | 58.8 (1.3) | 8.89 | (5.91 to 11.87) | <0.01‡ |
| class 5 Apathy* | 411 | 49.9 (0.7) | – | ||
| CDR | |||||
| 1* | 481 | 49.1 (0.8) | – | ||
| 2 | 500 | 54.6 (0.7) | 5.50 | (3.12 to 7.88) | <0.01‡ |
| 3 | 84 | 55.8 (2.0) | 6.71 | (1.92 to 11.50) | 0.01 |
| MMSE | |||||
| per unit | – | – | –0.12 | (–0.36 to 0.13) | 0.36 |
| Dementia diagnosis | |||||
| possible* | 304 | 53.7 (0.9) | – | ||
| probable | 761 | 51.5 (0.5) | –2.20 | (–4.20 to –0.20) | 0.03 |
| Caregiver characteristics | |||||
| Sex | |||||
| male* | 395 | 50.6 (0.9) | – | ||
| female | 670 | 53.1 (0.7) | 2.52 | (–0.07 to 5.11) | 0.06 |
| Age categories | |||||
| 30–59* | 250 | 55.7 (1.0) | – | ||
| 60–69 | 246 | 55.6 (1.0) | –0.03 | (–2.79 to 2.72) | 0.98 |
| 70–79 | 334 | 49.6 (0.9) | –6.11 | (–8.99 to –3.22) | <0.01‡ |
| 80–89 | 223 | 48.7 (1.1) | –6.94 | (–10.11 to –3.77) | <0.01‡ |
| 90+ | 12 | 44.6 (4.2) | –11.04 | (–19.72 to –2.36) | 0.01 |
| Education | |||||
| primary education or less* | 654 | 51.7 (0.6) | – | ||
| secondary education or more | 411 | 52.9 (0.8) | 1.15 | (–0.92 to 3.22) | 0.28 |
*Reference category. †Estimates obtained by fitting a linear regression model with all variables in the table. ‡Statistically significant p-values after Bonferroni correction (p < 0.002).