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. 2022 Sep 12;6(1):539–556. doi: 10.3233/ADR-220035

Fig. 1.

Fig. 1

Three subsequent stages of Alzheimer’s disease: preclinical AD, prodromal AD, and AD dementia. Pathological changes are indicated by a blue line on the graph and at the bottom of the figure. Cognitive symptoms are indicated by a purple line and at the bottom of the figure. Aβ and tau are the pathological biomarkers currently used for AD. Adapted from [19].