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. 2022 Sep 19;48(5):197. doi: 10.3892/or.2022.8412

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Copyright: © Chen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Roles of HMGB1 mRNA in the development of PCa and the correlation with the expression of AR mRNA, analysed using bioinformatics. (A) The levels of HMGB1 mRNA in normal PG and PCa were analysed using the Oncomine and GEPIA databases. (B) The levels of AR mRNA in normal PG and PCa were analysed using the Oncomine and GEPIA databases. (C) The correlation between the expression of HMGB1 mRNA and AR mRNA was detected by the GEPIA database. (D) The levels of AR mRNA and HMGB1 mRNA in VCaP, 22RV1, LNCaP, and MDAPCA2B cells were analysed using the DepMap Portal database. HMGB1, high-mobility group protein B1; PCa, prostate cancer; AR, androgen receptor; PG, prostate gland; PRAD, prostate adenocarcinoma.