Expression levels of HMGB1 and AR proteins in the specimens of patients with PCa detected by IHC staining. (A) The expression levels of HMGB1 protein in PCa specimens with different Gleason scores. (B) The expression levels of AR protein in PCa specimens with different Gleason scores. (C) The association between HMGB1 protein expression in the specimens with Gleason scores and PSA levels. (D) The association between AR protein expression in the specimens and Gleason scores and PSA levels. (E) The correlation between HMGB1 protein expression and AR protein expression in the specimens of the patients. *P<0.05. HMGB1, high-mobility group protein B1; AR, androgen receptor; PCa, prostate cancer; IHC, immunohistochemical; MOD, mean optical density.