Table 3. IC50 (μM) for Compounds 1 and 8.
cancerous
cell lines |
||||
---|---|---|---|---|
sample | U251 | K562 | HCT-15 | SKLU-1 |
(1) | 30.9 ± 1.3 | 18.8 ± 0.5 | 39.0 ± 2.9 | 39.9 ± 1.6 |
(8) | ND | 13.6 ± 0.7 | ND | ND |
etoposide | 2.4 ± 0.2 | 2.2 ± 0.7 | 4.8 ± 0.5 | 2.6 ± 0.3 |
ND: not determined. Human tumor cell lines: U251 (glioblastoma), K562 (leukemia), HCT-15 (colon), and SKLU-1 (lung).