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. 2022 Aug 18;23(10):e54520. doi: 10.15252/embr.202154520

Figure 5. PP1 and PP2A regulate transcription of protein‐coding genes.

Figure 5

  • A
    ChIP‐qPCR of total pol II after 30‐min treatment with DMSO, TT, CA, or LB‐100 on KPNB1. n = 3 biological replicates, mean ± SEM, P‐value: *P < 0.05, **P < 0.01, ***P < 0.001. Statistical test: two‐tailed unpaired t‐test.
  • B
    ChIP‐qPCR of total pol II after 30‐min treatment with DMSO, DRB, DRB + TT, DRB + CA, or DRB + LB‐100 on KPNB1. n = 3 biological replicates, mean ± SEM, P‐value: *P < 0.05, **P < 0.01, ***P < 0.001. Statistical test: two‐tailed unpaired t‐test.
  • C
    ChIP‐qPCR of total pol II after 30‐min treatment with DMSO or DRB + CA + TT on KPNB1. n = 3 biological replicates, mean ± SEM, P‐value: *P < 0.05, **P < 0.01, ***P < 0.001. Statistical test: two‐tailed unpaired t‐test.