Table 2. Contribution Rates of the 13 Compounds to the hTR-Agonist Activities in Site2 and Site3 (%)a.
| (%) | site2_Jun. | site2_Sep. | site3_EF |
|---|---|---|---|
| TRIAC | 119 | 100 | 95 |
| TETRAC | 4.4 | 10 | |
| GC-1 | 17 | ||
| T3 | 7.1 × 10–2 | ||
| T4 | 1.5 × 10–2 | 7.7 × 10–2 | 8.3 × 10–2 |
| DITPA | |||
| 3-Cl-T3 | 3.3 × 10–2 | ||
| rT3 | 2.1 × 10–2 | ||
| acetyl T4 | |||
| T1 | 4.0 × 10–4 | ||
| TCBPA | 1.5 × 10–4 | 1.4 × 10–4 | 3.3 × 10–4 |
| TBBPA | 6.2 × 10–5 | 5.5 × 10–5 | 5.9 × 10–4 |
| triclabendazole | |||
| TCRs | 124 | 110 | 111 |
Hyphen refers to not detected by LC–MS/MS, and the maximum contribution rates calculated from LOQ (%) are given below: TRIAC = 0.43, TETRAC = 0.25, GC-1 = 6.9 × 10–2, T3 = 2.1 × 10–3, T4 = 2.1 × 10–3, DITPA = 7.9 × 10–4, 3-Cl-T3 = 1.2 × 10–3, rT3 = 6.7 × 10–4, acetyl T4 = 2.0 × 10–4, T1 = 2.6 × 10–5, TCBPA = 1.3 × 10–5, TBBPA = 8.9 × 10–6, and triclabendazole = 5.2 × 10–7. All values are represented as the mean of three replicates (n = 3). These concentrations in the STP effluents quantified by LC–MS/MS have been shown in Table S7 (ng/L), and the hTR-agonist activities in the sites have been shown in Table S8. A comparison with the 13 compound concentrations as T3 equivalent and the hTR-agonist activities is shown in Table S10 (ng-T3 eq/L). TCR is the total contribution rate (%). The dose–response and standard curves by the yeast assay and LC–MS/MS, respectively, are shown in Figure S1.