Table 2.

Study flowchart.

Study procedures	Screening	Care and follow-up	Follow-up until 240 minutes after treatment
Informed consent	✓
Eligibility criteria (without pain assessment)	✓
Demographics	✓
History and management of endometriosis	✓
Typology of pain crises	✓
Baseline pain assessment (T0) (just before the start of Endocare or control treatment)		✓
Assessment of general status	✓	✓	✓
Endocare or control treatment		✓
Pain evolution (pain relief and intensity)		✓a	✓b
Satisfaction			✓b
Concomitant treatments		✓c	✓c
Adverse events		✓	✓

^aEvaluation 15 minutes (T15), 30 minutes (T30), 45 minutes (T45), and 60 (T60) minutes posttreatment.

^bEvaluation 240 minutes (T240) posttreatment.

^cIncludes rescue treatment if needed.