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The top figure (A) shows the anti-coherent case and the bottom figure (B) the coherent case. The red dotted line marks the Bonferroni significance threshold of 3.9 × 10−7 (0.05 divided by the 18453 genes tested and 7 traits). We observe Bonferroni significant enrichment for RA plus enrichments in vitamin D and calcium with p-values < 10−5.
