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. 2022 Oct 6;17(10):e0275796. doi: 10.1371/journal.pone.0275796

Table 1. Characteristics and exposure case count for patients with RD.

Parameters OPTUMEXTDOD IBMMDCR IBMCOM
RD cases (N) 13,654 4,214 23,113
Mean age (years) 59 72 51
Female (%) 41 42 43
Observation time in years (median) 5.5 5 5
Observation time in years (IQR) 4.96 3.64 5.89
Cases with FQ class exposure, N(%) 6,696 (49.04%) 2,444 (58%) 9,204 (39.82%)
Cases with FINTA exposure, N(%) 271 (1.98%) 34 (0.81%) 469 (2.03%)
Cases with Amoxicillin exposure, N(%) 4,271 (31.28%) 1,468 (34.84%) 7,716 (33.38%)
Cases with Azithromycin exposure, N(%) 3,450 (25.27%) 1,189 (28.22%) 6,382 (27.61%)
Cases with Trimethoprim without Sulfamethoxazole exposure, N(%) 1,112 (8.14%) 371 (8.8%) 2,220 (9.6%)
Cases with Trimethoprim with Sulfamethoxazole exposure, N(%) 1,301 (9.53%) 522 (12.39%) 2,705 (11.7%)