Figure 5. The 2016 American College of Cardiology/American Heart Association/Heart Failure Society of America heart failure guideline update on pharmacologic treatment for stage C heart failure with reduced ejection fraction. Data from reference 42 with permission.
ACE = angiotensin converting enzyme; ARNI = angiotensin receptor-neprilysin inhibitor; ARB = angiotensin receptor blocker; COR = class of recommendation; LOE = level of evidence; MYHA = New York Heart Association.