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Receiver-operating-characteristic curves (validation set) for pairwise (1 vs. 2) MLP-NN–based tissue discrimination (median of 5 iterations shown). After ComBat harmonization, areas under curve are clearly improved for individual radiomic feature classes and radiomic signatures. GLCM = gray-level cooccurrence matrix; GLH = gray-level histogram; GLRLM = gray-level run-length matrix; GLSZM = gray-level size-zone matrix; NGTDM = neighboring gray-tone difference matrix.
