TABLE 2.

Tissue Classification Based on Radiomic Feature Classes and Signatures in 4-Tissue Model

Classification accuracy	Unharmonized		Harmonized		P
	Median	Range	Median	Range
Gray-level histogram
Training	46.3	44.8–48.9	56.1	53.6–60.4	0.043
Validation	45.8	42.5–49.2	53.8	46.3–56.3	0.043
Gray-level cooccurrence matrix
Training	43.4	37.5–46.1	62.7	60.5–64.3	0.043
Validation	39.2	36.7–41.7	57.5	50.8–65.0	0.042
Gray-level run-length matrix
Training	46.3	43.4–47.1	63.0	57.3–64.5	0.042
Validation	41.7	40.4–47.9	59.2	52.5–61.7	0.043
Gray-level size-zone matrix
Training	43.4	41.4–43.8	86.0	83.0–87.5	0.043
Validation	39.6	36.3–42.9	82.5	68.8–85.0	0.043
Neighborhood gray-tone difference matrix
Training	42.1	39.6–45.0	62.7	60.0–64.3	0.043
Validation	42.5	36.7–46.7	61.3	57.1–65.8	0.043
Radiomic signature
Training	51.6	48.2–56.6	82.1	80.0–86.3	0.042
Validation	48.8	42.9–50.8	81.3	67.5–82.9	0.043

Data are percentages.