TABLE 2.

Patient- and Lesion-Based Analyses of ¹⁸F-PFPN and ¹⁸F-FDG PET Imaging Findings

Analysis	Parameter	Primary tumor	Lymph node metastases	Bone metastases	Liver metastases	Metastases to other sites
Patient-based analysis		8	18	8	7	6
Number of patients	18F-FDG	8	17	7	5	4
	18F-PFPN	8	18	8	7	6
	P		1.0*	1.0*	0.462*
Normalized SUVmax	18F-FDG	4.42 ± 3.43	7.36 ± 6.08	6.18 ± 4.06	4.94 ± 4.36	13.92 ± 10.97
	18F-PFPN, 1 h	10.27 ± 6.09	15.14 ± 14.07	18.21 ± 21.00	23.56 ± 25.66	20.32 ± 19.29
	18F-PFPN, 3 h	17.82 ± 10.29	21.10 ± 17.66	28.47 ± 36.08	37.03 ± 48.64	29.87 ± 27.1
	P (1 h/3 h)	0.022*/0.008*	0.043/0.005	0.161/0.130	0.144/0.178	0.496/0.211
Lesion-based analysis			124	394	141	33
Number of lesions	18F-FDG		98	151	49	29
	18F-PFPN		124	394	141	33
	P		0.000	0.000	0.000	0.114†
Normalized SUVmax	18F-FDG		5.36 ± 4.08	5.01 ± 2.33	5.08 ± 2.11	7.93 ± 7.70
	18F-PFPN, 1 h		10.88 ± 9.49	20.14 ± 21.83	19.17 ± 17.29	11.97 ± 11.59
	18F-PFPN, 3 h		16.35 ± 13.55	31.83 ± 37.09	31.55 ± 31.52	17.52 ± 16.56
	P (1 h/3 h)		0.000/0.000	0.000/0.000	0.000/0.000	0.117/0.006

^*Paired t test.

^†Fisher exact test.

1 h/3 h = P value calculated for ¹⁸F-FDG SUV_max vs. ¹⁸F-PFPN SUV_max at 1 or 3 h.