Table 1. Baseline characteristics of the included studies.
| Study | Data source | Sample size | CKD status | No. of patients | Mean age (year) | Man | White | Black | HTN | DM | BMI (kg/m2) | CHD | COPD | Stroke | PAD |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Bansal et al.5) | USRDS | 416 | ESRD | 155 | 58.4±12.1 | 59.4 | 59.4 | 37.4 | 98.1 | 72.9 | NR | 92.9 | 40.7 | 23.3 | 41.3 |
| No ESRD | 261 | 62.2±12.6 | 74.0 | 74.0 | 20.3 | 85.1 | 54.4 | NR | 90.8 | 43.7 | 20.3 | 23.8 | |||
| Kirklin et al.7) | INTERMACS | 4,917 | Severe (eGFR <30) | 282 | 61.8 | NR | NR | NR | NR | 44.0 | 24.6 | NR | NR | 0.5 | NR |
| Moderate (eGFR 30–59) | 1,475 | 62.3 | NR | NR | NR | NR | 43.2 | 26.6 | NR | NR | 1.0 | NR | |||
| Mild/none (eGFR >60) | 3,160 | 52.8 | NR | NR | NR | NR | 27.5 | 30.0 | NR | NR | 0.8 | NR | |||
| Mohamedali et al.8) | Single center | 213 | GFR <60 | 135 | 64±11 | 76 | 57 | 34 | 67 | 51.0 | 28±6 | 67 | 19 | 19 | 13 |
| GFR >60 | 78 | 56±14 | 82 | 45 | 46 | 65 | 36.0 | 28±7 | 54 | 12 | 17 | 10 | |||
| Sandner et al.6) | Single center | 86 | GFR <60 | 40 | 58.7±6.0 | 77.5 | NR | NR | 42.5 | 35.0 | 26.9±3.6 | NR | NR | NR | NR |
| GFR >60 | 46 | 47.3±12.7 | 91.3 | NR | NR | 21.7 | 26.1 | 26.1±3.7 | NR | NR | NR | NR | |||
| Kilic et al.10) | Single center | 238 | GFR <60 (DT) | 85 | 64±10 | 87 | 61 | NR | 67 | 48.0 | 29±6 | 66 | 21 | 11 | NR |
| GFR <60 (BTT) | 47 | 54±9 | 74 | 49 | NR | 72 | 57.0 | 30±6 | 53 | 6 | 19 | NR | |||
| GFR >60 (DT) | 54 | 57±16 | 81 | 63 | NR | 59 | 43.0 | 29±8 | 57 | 24 | 20 | NR | |||
| GFR >60 (BTT) | 49 | 46±15 | 78 | 53 | NR | 46 | 39.0 | 29±7 | 37 | 13 | 12 | NR | |||
| Doshi et al.11) | NIS | 20,656 | ESRD | 1,576 | 56.0±13.7 | 77.8 | 56.9 | 19.4 | 43.9 | 22.6 | NR | NR | 10.2 | NR | 11.5 |
| CKD stage IV–V | 751 | 61.7±11.3 | 84.9 | 54.9 | 27.7 | 39.8 | 26.2 | NR | NR | 15.1 | NR | 7.9 | |||
| No CKD/CKD stage I–III | 18,329 | 55.9±13.5 | 76.3 | 58.7 | 20.7 | 43.4 | 25.7 | NR | NR | 18.9 | NR | 8.6 | |||
| Ajmal et al.12) | Single center | 126 | GFR <60 | 84 | 61±12 | 82 | NR | NR | 82 | 54.0 | 28.6 | NR | 19 | 22 | 6 |
| GFR >60 | 42 | 56±14 | 79 | NR | NR | 66 | 40.0 | 29.1 | NR | 17 | 24 | 5 |
Values are mean±standard deviation or number (%).
CKD = chronic kidney disease; ESRD = end stage renal disease; eGFR = estimated glomerular filtration rate; NR = not reported; GFR = glomerular filtration rate (units are mL/min/1.73 m2); HTN = hypertension; DM = diabetes mellitus; BMI = body mass index; CHD = coronary heart disease; COPD = chronic obstructive lung disease; PAD = peripheral artery disease; USRDS = United States renal data system; INTERMACS = Interagency Registry for Mechanically Assisted Circulatory Support; NIS = national inpatient sample; DT = destination therapy; BTT = bridge to transplantation.