Table 1. Favorable donor characteristics.
| Criteria for favorable donor for heart transplantation | |
|---|---|
| Age (<55 years) | |
| Absence of significant structural abnormalities such as: | |
| LV hypertrophy (wall thickness >13 mm by echocardiography) | |
| Significant valvular dysfunction | |
| Significant congenital cardiac abnormality | |
| Significant coronary artery disease | |
| Adequate physiologic function of donor heart | |
| LVEF ≥45% or | |
| Achievement of target hemodynamic criteria after hormonal resuscitation and hemodynamic management | |
| MAP >60 mmHg | |
| PCWP 8–12 mmHg | |
| Cardiac index >2.4 L/min·m2 | |
| CVP 4–12 mmHg | |
| SVR 800–1,200 dyne/s·cm5 | |
| No inotrope dependence | |
| Donor-recipient body size match (usually within 20–30% of height and weight) | |
| Negative hepatitis C antibody, hepatitis B surface antigen, and HIV serologies absence of active malignancy (except non-melanoma skin cancers and certain primary brain tumors) or overwhelming infection | |
Adopted from reference 3.
CVP = central venous pressure; HIV = human immunodeficiency virus; LV = left ventricle; LVEF = left ventricle ejection fraction; MAP = mean arterial pressure; PCWP = pulmonary capillary wedge pressure; SVR = systemic vascular resistance.