Figure 2. Surgical Intervention is Significantly More Efficacious at Lowering Body Weight and ICP Than Diet Weight Loss Intervention.

Percentage change in diet and surgery groups at baseline, 12-month, and 24-month timepoints for (A) body weight; (B) intracranial pressure; (C) papilledema as measured by OCT volume central thickness; (D) monthly headache days; (E) headache severity; and (F) HIT-6 score; data presented as mean ± SEM. Statistical significance was determined by hierarchical regression modeling in accordance with per-protocol analysis. ***p < 0.001. CWI = community weight management intervention; HIT-6 = headache impact test-6; ICP = intracranial pressure; OCT = optical coherence tomography.