Table 2.

Differences of FA values in the WM tracts between patients with MDD and HC

WM tracts	MDD	HC	F value	p
Forceps major	0.589±0.027	0.594±0.041	1.574	0.213
Forceps minor	0.475±0.036	0.493±0.038	0.619	0.433
L ATR	0.420±0.034	0.425±0.028	4.310	0.041
L CAB	0.378±0.052	0.376±0.032	10.597	0.002*
L CCG	0.564±0.043	0.568±0.036	0.485	0.488
L CST	0.545±0.030	0.545±0.026	0.880	0.351
L ILF	0.477±0.030	0.484±0.029	0.106	0.745
L SLFp	0.429±0.024	0.441±0.027	0.122	0.727
L SLFt	0.459±0.022	0.469±0.025	0.526	0.470
L UF	0.426±0.031	0.436±0.027	1.523	0.221
R ATR	0.419±0.034	0.424±0.032	0.329	0.568
R CAB	0.411±0.051	0.401±0.042	2.225	0.139
R CCG	0.582±0.037	0.571±0.047	2.153	0.146
R CST	0.559±0.030	0.552±0.029	0.168	0.683
R ILF	0.492±0.029	0.496±0.029	0.251	0.617
R SLFp	0.447±0.028	0.453±0.030	0.121	0.729
R SLFt	0.458±0.024	0.461±0.023	0.081	0.777
R UF	0.450±0.037	0.454±0.025	4.337	0.040

Data are presented as mean±standard deviation. The F and p-values were obtained using one-way analysis of covariance adjusted for age and sex as covariates. The Bonferroni correction was applied in 18 WM tracts: 18 comparisons in both hemispheres, p<0.00278 (0.05/18).s

^*denotes WM tracts that remained significant after Bonferroni correction.

FA, fractional anisotropy; WM, white matter; MDD, major depressive disorder; HC, healthy control; L, left hemisphere; R, right hemisphere; ATR, anterior thalamic radiation; CAB, cingular-angulum bundle; CCG, cingulum–cingulate gyrus bundle; CST, corticospinal tract; ILF, inferior longitudinal fasciculus; SLFp, superior longitudinal fasciculus–parietal bundle; SLFt, superior longitudinal fasciculus–temporal bundle; UF, uncinate fasciculu