Table 2.

A comparison of Illumina production scale sequencer sequencers [29].

Methods/applications	NextSeq 550	NextSeq 550Dx	NextSeq 1000 & 2000	NovaSeq 6000
Ideal for	Research	Research+in vitro diagnostic	Targeted sequencing	Long read applications
Major applications	sWGS (microbes), TGS, and TCS	NextSeq 550+clinical NGS applications	NextSeq 550 series+SCP	NextSeq 550 series+NextSeq 1000 & 2000+lWGS
Max. data quality	>80% > Q30	>75% > Q30	>90% > Q30	>90% > Q30
Run time	12-30 hours	35 hours	11-48 hours	13-44 hours
Maximum output	120 Gb	90 Gb	360 Gb	6000 Gb
Maximum reads per run	400 million	300 million	1.2 billion	20 billion
Maximum read length	2 × 150 bp	2 × 150 bp	2 × 150 bp	2 × 250 bp