Figure 6.

Comparison of ex vivo AFM and in vivo MRE results. (A) Stiffness increases with greater distance (in µm) from the peak of the fluorescence signal (marked as 0), 0 µm vs. 100 µm **p = 0.0025; 0 µm vs. 200 µm ****p < 0.0001; 0 µm vs. 300 µm **p = 0.0069, 0 µm n = 15, 100 µm n = 15, 200 µm n = 15, 300 µm n = 10, 400 µm n = 5. (B) Similar results are seen in vivo when the dentate gyrus mask is eroded: original mask (0 µm) vs. 2 pixel eroded mask (140 µm), *p = 0.0309, eroded original mask (0 µm) vs. 3 pixels eroded mask (210 µm), **p = 0.0043; 1 pixel eroded (70 µm) vs. 2 pixel eroded mask (140 µm), **p = 0.0051; 1 pixel eroded (70 µm) vs. 3 pixel eroded mask (210 µm), ***p = 0.0005; 2 pixel eroded (140 µm) vs. 3 pixel eroded mask (210 µm), **p = 0.0069), n = 10.