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. 2022 Oct 6;12:16693. doi: 10.1038/s41598-022-21050-5

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Functional enrichment analysis of DEGs. The P value represents the colour depth of the node. The size of the node implies the number of DEGs. (a) GO functional enrichment analysis results for DEGs, including Biological process(BP), molecular function(MF) and cellular component(CC). (b) KEEG enrichment analysis reveals signalling pathways highly relevant to NSCLC. (c) DO functional enrichment analysis results of DEGs. (d) GSEA shows the top six signalling pathways most associated with normal lung tissue. (e) GSEA shows the top six signalling pathways most associated with NSCLC.