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. 2022 Oct 6;12:16677. doi: 10.1038/s41598-022-20357-7

Table 2.

Hazard ratios (HRs) for the association between SUA and the risk of CRC.

Group Cases/person-years Crude models Adjusted models
HR (95%CI) p-value HR (95%CI) p-value
Traditional Cox models
T1 group 164/385,559 Ref Ref
T2 group 188/383,406 1.47 (1.02, 2.01) 0.044 1.13 (0.92, 1.67) 0.435
T3 group 231/373,106 2.30 (1.53, 3.40)  < 0.001 1.55 (1.09, 2.30) 0.019
P for trend  < 0.001 0.004
SD models
T1 group 164/385,559 Ref Ref
T2 group 188/383,406 1.44 (0.99, 2.01) 0.057 1.07 (0.87, 1.56) 0.510
T3 group 231/373,106 2.29 (1.52, 3.40)  < 0.001 1.50 (1.05, 2.25) 0.029
P for trend  < 0.001 0.005
CS models
T1 group 164/385,559 Ref Ref
T2 group 188/383,406 1.47 (1.02, 2.01) 0.045 1.13 (0.91, 1.67) 0.460
T3 group 231/373,106 2.29 (1.53, 3.39)  < 0.001 1.55 (1.09, 2.30) 0.020
P for trend  < 0.001 0.005

Models were adjusted for age (every 10 years), sex, family income, educational background, marital status, BMI, TG, TC, TBIL, ALT, CRP, smoking status, drinking status, physical activity, sedentary lifestyle, tea consumption, high-fat diet, diabetes, hypertension, chronic kidney disease, and family history of cancer.

SD models: the sub-distribution hazard function models.

CS models: the cause-specific hazards models.