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. 2022 Oct 6;12:16677. doi: 10.1038/s41598-022-20357-7

Table 4.

Sensitivity analysis after excluding participants who occurred cancer within the first year and the first five years of follow-up.

Groups Cases/person-years Adjusted models
HR (95%CI) p-value
Exclude CRC cases diagnosed within the first year of follow-up
T1 group 153/385,550 Ref
T2 group 178/383,401 1.09 (0.88, 1.68) 0.655
T3 group 224/373,103 1.57 (1.11, 2.31) 0.014
P for trend 0.001
Exclude CRC cases diagnosed within the first 5 year of follow-up
T1 group 68/385,252 Ref
T2 group 90/383,063 1.22 (0.92, 2.39) 0.351
T3 group 140/372,806 2.01 (1.58, 2.89)  < 0.001
P for trend  < 0.001

Models were adjusted for age (every 10 years), sex, family income, educational background, marital status, BMI, TG, TC, TBIL, ALT, CRP, smoking status, drinking status, physical activity, sedentary lifestyle, tea consumption, high-fat diet, diabetes, hypertension, chronic kidney disease, and family history of cancer.