Table 3:
Logistic Regression of Maternal Variables in NICU Registry with BPD Status
| Pregnancy Exposures and Complications | BPD | Controls | aOR | 95% CI | p-value |
|---|---|---|---|---|---|
| Multiple gestation, N (%) | 308 (22%) | 741 (24%) | 1.06 | 0.85 – 1.33 | 0.59 |
| Prenatal Care, N (%) | 1328 (96%) | 3013 (96%) | 1.84 | 1.14 – 3.01 | 0.01 |
| Vaginal Bleeding, N (%) | 322 (23%) | 432 (14%) | 1.04 | 0.81 – 1.34 | 0.73 |
| Chorioamnionitis, N (%) | 174 (13%) | 290 (9%) | 0.89 | 0.76 – 1.03 | 0.13 |
| Oligohydramnios, N (%) | 79 (6%) | 119 (4%) | 2.19 | 1.42 – 3.34 | 3.3 × 10−4* |
| Polyhydramnios, N (%) | 23 (2%) | 40 (1%) | 5.70 | 2.78 – 11.44 | 1.4 × 10−6* |
| Diabetes (all types), N (%) | 142 (10%) | 385 (11%) | 1.69 | 1.25 – 2.27 | 5.8 × 10−4* |
| Chronic Hypertension, N (%) | 174 (13%) | 290 (9%) | 1.14 | 0.86 – 1.51 | 0.37 |
| Maternal Drug Use, N (%) | 369 (27%) | 820 (24%) | 0.85 | 0.68 – 1.05 | 0.123 |
| Antenatal Steroids, N (%) | 1162 (84%) | 2523 (80%) | 1.14 | 0.85 – 1.51 | 0.39 |
| C-section, N (%) | 1024 (74%) | 2001 (64%) | 1.81 | 1.46 – 2.26 | 1.1 × 10−7* |
| Vertex Presentation, N (%) | 832 (60%) | 2369 (75%) | 0.77 | 0.63 – 0.94 | 0.01 |
| Anesthesia used in labor, N (%) | 1213 (88%) | 2830 (83%) | 1.31 | 0.96 – 1.81 | 0.09 |
| Pre-eclampsia, N (%) | 317 (23%) | 819 (26%) | 1.07 | 0.85 – 1.34 | 0.59 |
| Placenta abruption, N (%) | 218 (16%) | 271 (9) | 1.14 | 0.85 – 1.52 | 0.38 |
| Meconium, N (%) | 55 (4%) | 130 (4%) | 0.97 | 0.61 – 1.53 | 0.90 |
| Mom Age, mean (SD) | 26.8 (6.18) | 26.7 (5.94) | 1.02 | 1.00 – 1.03 | 0.22 |
| Gravida, mean (SD) | 2.7 (1.9) | 2.6 (1.8) | 1.00 | 0.97 – 1.01 | 0.98 |
| Preterm Premature Rupture of Membranes, (N (%) | 143 (10) | 426 (12) | 1.01 | 0.74 – 1.37 | 0.94 |
| Rupture of membranes (days), mean (SD) | 2.3 (8.5) | 1.4 (4.9) | 1.03 | 1.02 – 1.05 | 5.4 × 10−7* |
(*)
indicates statistical significance based on Bonferroni threshold (with adjustment for gestational age, birthweight, sex, maternal race, birth year and birth location)