Table 3:

Multivariable associations of cardiovascular risk factors with CIMT and IM-GSM

Risk factors	CIMT (μm)			IM-GSM
	R2=0.21			R2=0.26
	β-estimate	(SE)	p-value	β-estimate	(SE)	p-value
Age, years	4.65	(0.56)	<.0001	−0.226	(0.06)	0.0001
Race (%)
White non-Hispanic	ref			ref
Black non-Hispanic	27.78	(13.54)	0.04	−1.715	(1.437)	0.23
Hispanic	−20.99	(11.31)	0.06	−2.802	(1.197)	0.02
Asian	−3.831	(14.13)	0.79	−2.690	(1.461)	0.07
Body mass index, kg/m2	2.95	1(.109)	0.008	−0.815	(0.116)	<.0001
Physical activity, MET hours/week				0.037	(0.018)	0.049
LDL-cholesterol, mg/dl	0.24	(0.12)	0.05	−0.026	(0.013)	0.04
HDL-cholesterol, mg/dl	−0.25	(0.24)	0.30	0.015	0.029)	0.59
Triglycerides, mg/dl				−0.005	0.009	0.60
Systolic blood pressure, mmHg	1.70	(0.32)	<.0001	−0.076	0.034	0.02
†Diastolic blood pressure, mmHg	1.17	(0.58)	0.04	−0.075	(0.06)	0.19
‡Antihypertensive medication use	0.82	(9.59)	0.93	−1.78	(0.10)	0.07
Glucose, mg/dl	−0.001	(0.39)	0.90	−0.076	(0.04)	0.06
±Leptin, ng/ml	−0.11	(0.29)	0.70	−0.099	(0.03)	0.002
Adiponectin, μg/ml				0.049	(0.06)	0.44
Ghrelin, pg/ml				−0.0003	(0.001)	0.76
IL-6, pg/ml	5.72	(3.12)	0.07	−0.59	(0.32)	0.07
ICAM-1, ng/ml	0.02	(0.06)	0.68	−0.0004	(0.006)	0.95
E-selectin, ng/ml				−0.075	(0.04)	0.08

Risk factors significantly (p-value<0.05) associated in the univariate analysis were included in the multivariate model for each outcome

^†Results from separate model replacing SBP with DBP, R² = 0.26 for IM-GSM, R² = 0.18 for CIMT model

^‡Results from separate model not including SBP and DBP, R² = 0.20 for IM-GSM, R² = 0.18 for CIMT model

^±Results from separate model not including BMI, R² = 0.20 for IM-GSM, R² = 0.20 for CIMT model