Table 4:
CIMT (μm) | IM-GSM (unitless) | |||
---|---|---|---|---|
Beta (SE) | P-value | Beta (SE) | P-value | |
Model 1: | ||||
*Basic demographic model + lipids | R2difference =0.01 | †R2difference = 0.02 | ||
HDL-cholesterol, mg/dl | −0.35 (0.27) | 0.19 | 0.02 (0.03) | 0.36 |
LDL-Cholesterol, mg/dl | 0.33 (0.13) | 0.01 | −0.03 (0.01) | 0.01 |
Triglycerides, mg/dl | −0.10 (0.09) | 0.24 | −0.01 (0.01) | 0.33 |
Model 2: | R2difference = 0.01 | R2difference = 0.01 | ||
Basic demographic model + diastolic blood pressure (DBP) | ||||
DBP, mmHg | 1.61 (0.56) | 0.004 | −0.14 (0.06) | 0.01 |
Model 3: | R2difference = 0.04 | R2difference = 0.02 | ||
Basic demographic model + systolic blood pressure (SBP) | ||||
SBP mmHg | 1.89 (0.32) | <0.0001 | −0.11 (0.03) | 0.0006 |
Model 4: | R2difference = 0.001 | R2difference = 0.01 | ||
Basic demographic model + Glucose | ||||
Glucose, mg/dl | 0.27 (0.38) | 0.49 | −0.10 (0.04) | 0.008 |
Model 5: | ||||
Basic demographic model + Inflammatory markers | R2difference = 0.005 | R2difference = 0.013 | ||
Il_6, pg/ml | 6.05 (3.21) | 0.06 | −0.53 (0.32) | 0.10 |
ICAM-1, ng/ml | 0.05 (0.06) | 0.42 | −0.002 (0.006) | 0.74 |
E-selectin, ng/ml | −0.16 (0.42) | 0.71 | −0.09 (0.04) | 0.03 |
Model 6‡: | ||||
Basic demographic model + Adipokines | R2difference = 0.01 | R2difference = 0.07 | ||
Leptin, ng/ml | 0.32 (0.29) | 0.27 | −0.16 (0.003) | <.0001 |
Adiponectin, μg/ml | −1.06 (0.58) | 0.07 | 0.16 (0.06) | 0.01 |
Ghrelin, pg/ml | −0.005 (0.01) | 0.61 | 0.0002 (0.001) | 0.08 |
Basic demographic model includes age race, BMI, and MET (R2= 0.16 for CIMT and 0.22 for IM-GSM)
(R2 of each model – R2 of basic demographic model)
Basic demographic model includes age, race, and MET (R2= 0.14 for CIMT and 0.08 for IM-GSM)