TABLE 2.
Differentially expressed small ncRNAs in senescent fibroblast derived EVs compared to non-senescent control EVs.
| RNA Type | Gene Reference | Log (Fold Change) | p-value |
|---|---|---|---|
| lncRNA | Homo sapiens (human) non-protein coding lnc-JPH3-2:1 | −9.16986 | 0.000363 |
| lncRNA | Homo sapiens (human) non-protein coding lnc-OSMR-2:1 | 6.970119 | 0.001103 |
| lncRNA | Homo sapiens (human) non-protein coding lnc-SHANK1-1:1 | −7.16186 | 0.005861 |
| lncRNA | Homo sapiens (human) non-protein coding lnc-ERMARD-2:1 | −6.84115 | 0.012497 |
| lncRNA | Homo sapiens (human) non-protein coding lnc-CAGE1-1:5 | −6.44395 | 0.018785 |
| lncRNA | Homo sapiens (human) non-protein coding lnc-C9orf135-2:2 | 4.207866 | 0.020931 |
| lncRNA | Homo sapiens (human) non-protein coding lnc-RAB9B-2:1 | −6.35022 | 0.02106 |
| lncRNA | Homo sapiens (human) non-protein coding lnc-RAI2-2:1 | 6.041448 | 0.02992 |
| lncRNA | Homo sapiens (human) non-protein coding lnc-SFMBT1-5:1 | 5.984509 | 0.032055 |
| lncRNA | Homo sapiens (human) non-protein coding lnc-ADGRF3-3:1 | −5.94978 | 0.034132 |
| lncRNA | Homo sapiens (human) non-protein coding lnc-METTL2B-3:7 | 4.738157 | 0.038586 |
| tRNA | Homo sapiens transfer RNA-Val (AAC) 4-1 (TRV-AAC4-1) | 5.39902 | 0.000755 |
| tRNA | Homo sapiens transfer RNA-Glu (TTC) 3-1 (TRE-TTC3-1) | 4.978853 | 0.001346 |
| tRNA | Homo sapiens transfer RNA-Val (CAC) 5-1 (TRV-CAC5-1) | −4.73597 | 0.001869 |
| tRNA | Homo sapiens (human) tRNA-Lys | −4.90269 | 0.002975 |
| tRNA | tRNA3Lys from Homo sapiens (PDB 5CD1, chain M) | -4.39151 | 0.005317 |
| tRNA | Homo sapiens transfer RNA-Ala (AGC) 2-1 (TRA-AGC2-1, TRA-AGC2-2, TRA-AGC7-1) | 5.65347 | 0.007501 |
| tRNA | Homo sapiens transfer RNA-Lys (TTT) 5-1 (TRK-TTT5-1) | 3.728341 | 0.011775 |
| tRNA | Homo sapiens transfer RNA-Glu (TTC) 4-1 (TRE-TTC4-1, TRE-TTC4-2) | 3.6769 | 0.013233 |
| tRNA | Homo sapiens transfer RNA-Ala (CGC) 4-1 (TRA-CGC4-1) | 4.048057 | 0.016309 |
| tRNA | Homo sapiens (human) transfer RNA-Glu | -3.29739 | 0.021338 |
| tRNA | Homo sapiens tRNA | -3.33278 | 0.021851 |
| tRNA | Homo sapiens transfer RNA-Cys (GCA) 2-1 (TRC-GCA2 1–4) | -3.58043 | 0.033819 |
| tRNA | Homo sapiens tRNA Gly GCC | -3.23536 | 0.039213 |
| snoRNA | Homo sapiens (human) small nucleolar RNA, C/D box 33 (SNORD33) | 1.341 | 0.2766 |