Table 3.
Hazard ratios and 95% confidence intervals for time to dementia.
| Main analysis | E-value | Sens. analysis 1 | E-value | Sens. analysis 2 | E-value | ||
|---|---|---|---|---|---|---|---|
| HR (95% CI) | Lower limit | HR (95% CI) | Lower limit | HR (95% CI) | Lower limit | ||
| Full population | Crude | 3.6 (3.1–4.2) | 6.7 (5.7) | 3.5 (3.0–4.2) | 6.5 (5.5) | 4.7 (4.0–5.5) | 8.9 (7.5) |
| Adjusted | 3.7 (3.2–4.3) | 7.1 (5.9) | 3.7 (3.1–4.3) | 7.1 (5.7) | 4.8 (4.1–5.7) | 9.1 (7.7) | |
| Hoehn & Yahr ≤ 2.0 | Crude | 3.1 (2.4–4.1) | 5.1 (4.2) | 3.0 (2.3–3.9) | 5.5 (4.0) | 3.6 (2.7–4.7) | 6.7 (4.8) |
| Adjusted | 3.4 (2.6–4.5) | 6.3 (4.6) | 3.1 (2.3–4.1) | 5.7 (4.0) | 3.7 (2.8–5.0) | 6.9 (5.0) | |
| Hoehn & Yahr > 2.0 | Crude | 5.1 (4.1–6.4) | 9.7 (7.7) | 4.3 (3.5–5.4) | 8.1 (6.5) | 6.2 (5.0–7.7) | 11.9 (9.5) |
| Adjusted | 5.4 (4.3–6.8) | 10.3 (8.1) | 4.4 (3.5–5.6) | 8.3 (6.5) | 6.1 (4.9–7.7) | 11.7 (9.3) | |
HR hazard ratio, CI confidence interval, Sens. analysis 1 2 or more records of a dementia coded event, Sens. analysis 2 dementia defined prescribed a N06D anti-dementia drug.