Table 2.
TNM stage Stage I is referent |
Univariable analysis | Multivariable analysis | ||||
---|---|---|---|---|---|---|
Stage II OR (95% CI) |
Stage III OR (95% CI) |
Stage IV OR (95% CI) |
Stage II OR (95% CI) |
Stage III OR (95% CI) |
Stage IV OR (95% CI) |
|
Males | ||||||
BMIa, kg/m2 | 1.02 (0.95–1.09) | 0.93 (0.87–0.98)* | 0.90 (0.86–0.95)*** | 1.09 (0.95–1.25) | 0.97 (0.87–1.08) | 1.03 (0.93–1.14) |
VATa, per 10 cm2 | 0.99 (0.96–1.01) | 0.97 (0.95–0.99)* | 0.94 (0.92–0.96)*** | 0.97 (0.93–1.00) | 0.98 (0.95–1.01) | 0.93 (0.91–0.96)*** |
SATa, per 10 cm2 | 1.01 (0.97–1.04) | 0.97 (0.94–1.00) | 0.96 (0.94–0.99)* | 0.99 (0.94–1.05) | 1.00 (0.96–1.05) | 1.01 (0.96–1.05) |
TATb, per 10 cm2 | 1.00 (0.98–1.01) | 0.98 (0.97–1.00)* | 0.97 (0.95–0.98)*** | 0.97 (0.94–1.01) | 0.98 (0.96–1.01) | 0.95 (0.93–0.98)*** |
rVATb, in % | 0.99 (0.97–1.01) | 0.99 (0.98–1.01) | 0.97 (0.96–0.98)*** | 0.99 (0.97–1.01) | 0.99 (0.98–1.01) | 0.97 (0.96–0.99)*** |
Females | ||||||
BMIa, kg/m2 | 0.96 (0.88–1.03) | 0.96 (0.90–1.03) | 0.91 (0.86–0.97)** | 0.99 (0.85–1.15) | 1.01 (0.89–1.15) | 0.99 (0.88–1.11) |
VATa, per 10 cm2 | 0.97 (0.93–1.02) | 0.98 (0.94–1.02) | 0.95 (0.92–0.99)** | 0.98 (0.91–1.06) | 0.96 (0.90–1.02) | 0.95 (0.89–1.00)* |
SATa, per 10 cm2 | 0.98 (0.94–1.01) | 0.98 (0.95–1.01) | 0.96 (0.93–0.98)** | 0.99 (0.93–1.05) | 1.00 (0.94–1.05) | 0.99 (0.94–1.03) |
TATb, per 10 cm2 | 0.99 (0.96–1.01) | 0.99 (0.97–1.01) | 0.97 (0.96–0.99)*** | 0.99 (0.94–1.03) | 0.98 (0.94–1.02) | 0.97 (0.94–1.00) |
rVATb, in % | 0.99 (0.97–1.02) | 1.00 (0.97–1.02) | 0.99 (0.97–1.01) | 0.99 (0.96–1.02) | 0.99 (0.96–1.01) | 0.98 (0.96–1.00) |
Fuhrman grade Grade 1 is referent |
Univariable analysis | Multivariable analysis | ||||
---|---|---|---|---|---|---|
Grade 2 OR (95% CI) |
Grade 3 + 4 OR (95% CI) |
Grade 2 OR (95% CI) |
Grade 3 + 4 OR (95% CI) |
|||
Males | ||||||
BMIa, kg/m2 | 1.03 (0.98–1.08) | 0.99 (0.94–1.04) | 0.96 (0.88–1.06) | 0.98 (0.89–1.08) | ||
VATa, per 10 cm2 | 1.01 (1.00–1.03) | 0.99 (0.97–1.00) | 1.03 (1.00–1.05) | 0.99 (0.96–1.02) | ||
SATa, per 10 cm2 | 1.02 (0.99–1.05) | 1.01 (0.98–1.03) | 1.01 (0.97–1.05) | 1.02 (0.98–1.06) | ||
SATa, high vs low | 1.51 (1.03–2.22)* | 0.95 (0.65–1.38) | 1.14 (0.72–1.82) | 0.94 (0.60–1.47) | ||
TATb, per 10 cm2 | 1.01 (1.00–1.02) | 0.99 (0.98–1.01) | 1.02 (1.00–1.05) | 1.00 (0.98–1.02) | ||
rVATb, in % | 1.00 (0.99–1.01) | 0.99 (0.97–1.00) | 1.01 (0.99–1.02) | 0.99 (0.94–1.05) | ||
Females | ||||||
BMIa, kg/m2 | 1.02 (0.97–1.07) | 0.98 (0.93–1.03) | 0.97 (0.88–1.07) | 1.02 (0.92–1.14) | ||
VATa, per 10 cm2 | 1.01 (0.98–1.04) | 0.97 (0.94–1.01) | 1.03 (0.98–1.08) | 1.00 (0.95–1.05) | ||
SATa, per 10 cm2 | 1.01 (0.99–1.04) | 0.99 (0.96–1.01) | 1.01 (0.97–1.05) | 0.98 (0.93–1.02) | ||
SATa, high vs low | 1.39 (0.87–2.22) | 0.59 (0.36–0.98)* | 1.10 (0.59–2.06) | 0.51 (0.26–0.99)* | ||
TATb, per 10 cm2 | 1.01 (0.99–1.02) | 0.99 (0.97–1.01) | 1.02 (0.99–1.05) | 0.99 (0.96–1.02) | ||
rVATb, in % | 0.99 (0.97–1.01) | 0.98 (0.97–1.00) | 1.00 (0.98–1.02) | 1.00 (0.98–1.03) |
BMI, body mass index; VAT, visceral adipose tissue; SAT, subcutaneous adipose tissue; TAT, total adipose tissue; rVAT, relative visceral adipose tissue; OR, odds ratio; CI, confidence interval.
*p-value < 0.05; **p-value < 0.01; ***p-value < 0.001.
aMultivariable models are adjusted for age and mutually adjusted for BMI, VAT and SAT; bMultivariable models are adjusted for age and BMI.