TABLE 5.
Quantitative results of LS-102 and AGS IV on SV-BA spacing after astemizole induction in zebrafish (n = 10).
Inducer concentrations (µM) | Groups | Concentrations (µg/ml) | SV-BA spacing (µm) (Mean±SE) | ||
---|---|---|---|---|---|
2 h | 6 h | 24 h | |||
4 | Control | − | 150 ± 4 | 149 ± 5 | 164 ± 3 |
Model | − | 206 ± 5*** | 236 ± 5*** | 251 ± 6*** | |
AGS IV | 250 | 210 ± 4*** | 242 ± 7** | 241 ± 4** | |
LS-102 | 27.8 | 179 ± 7* | 204 ± 6 | 250 ± 6** | |
83.3 | 157 ± 3 | 168 ± 4** | 228 ± 7* | ||
250 | 151 ± 3 | 158 ± 6** | 174 ± 9 |
* p < 0.05.
** p < 0.01.
*** p < 0.001, vs. Control group.