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. 2022 Sep 23;9:1000846. doi: 10.3389/fcvm.2022.1000846

Table 3.

Study of cardiotoxicity at T3 according to the different criteria, in patients of both groups (TG and CG).

Overall population Training group Control group
n = 75 n = 42 n = 33
n %(90%CI) n %(90%CI) n %(90%CI)
Cardiotoxicity (Criterion 1)
Yes 10 13.3 (7.4–21.6) 4 9.5 (3.3–20.5) 6 18.2 (8.2–32.8)
No 65 86.7 (78.4–92.6) 38 90.5 (79.5–96.7) 27 81.8 (67.2–91.8)
If yes, reason ?
Absolute decrease of at least 10% 8 80.0 4 100 4 66.7
LVEF at T3 < 50% 2 20.0 0 0.0 2 33.3
Cardiotoxicity (Criterion 2)
Yes 4 5.3 (1.8–11.8) 1 2.4 (0.0–10.8) 3 9.1 (2.5–21.8)
No 71 94.7 (88.2–98.2) 41 97.6 (89.2–100) 30 90.9 (78.2–97.5)
If yes, reason?
Absolute decrease of at least 15% 2 50.0 1 100 1 33.3
LVEF at T3 < 50% 2 50.0 0 0.0 2 66.7
Cardiotoxicity (Criterion 3)
Yes 2 2.7 (0.5–8.2) 0 0.0 (0.0–7.0) 2 6.1 (1.1–17.9)
No 73 97.3 (91.8–99.5) 42 100 (93.0–100) 31 93.9 (82.1–98.9)
Cardiotoxicity (Criterion 4)
Yes 10 22.7 4 16.7 6 30.0
No 34 77.3 20 83.3 14 70.0
Missing 31 - 18 - 13 -

LVEF, left ventricular ejection fraction.