Table 2.
Top 10 predicted transcription factors (TFs) for the hub genes.
| Rank | TF | Score | Library | Overlapping_genes |
|---|---|---|---|---|
| 1 | LTF | 1 | ARCHS4 coexpression, 1; GTEx coexpression, 1 | CEACAM3, CEACAM1, ANXA3, ARG1, CYP4F3, CHI3L1, PADI2, RGL4, MMP8, ABCA13 |
| 2 | CREB5 | 34.67 | ARCHS4 coexpression, 30; Enrichr queries, 46; GTEx coexpression, 28 | CEACAM3, ANXA3, CYP4F3, RGL4 |
| 3 | CREB3L3 | 39.33 | ARCHS4 coexpression, 5; Enrichr queries, 106; GTEx coexpression, 7 | BTNL8, CEACAM1, ARG1, CYP4F3, HP |
| 4 | NFE4 | 51 | GTEx coexpression, 51 | CEACAM3, RGL4 |
| 5 | NR1H4 | 53.33 | ARCHS4 coexpression, 40; Enrichr queries, 80; GTEx coexpression, 40 | CEACAM1, ARG1, CYP4F3, HP |
| 6 | ATF5 | 54.67 | ARCHS4 coexpression, 50; Enrichr queries, 108; GTEx coexpression, 6 | ARG1, ANXA3, CYP4F3, HP |
| 7 | ZNF438 | 66.33 | ARCHS4 coexpression, 64; Enrichr queries, 104; GTEx coexpression, 31 | CEACAM3, ANXA3, GPR84, RGL4 |
| 8 | TBX10 | 68.67 | ARCHS4 coexpression, 35; Enrichr queries, 66; GTEx coexpression, 105 | BTNL8, CEACAM1, PADI2 |
| 9 | HNF4A | 73 | Literature ChIP-seq, 67; ARCHS4 coexpression, 7; ENCODE ChIP-seq, 18; Enrichr queries, 90; ReMap ChIP-seq, 104; GTEx coexpression, 152 | BTNL8, CEACAM1, ARG1, CYP4F3, HP |
| 10 | NR1I2 | 81.75 | Literature ChIP-seq, 13; ARCHS4 coexpression, 2; Enrichr queries, 144; GTEx coexpression, 168 | BTNL8, CEACAM1, ARG1, CYP4F3, HP |