Table 4.
Functional enrichment involving renal and urological disease for differentially expressed proteins.
| Categories | Functions | Diseases or functions annotation | p value | Molecules | # molecules |
|---|---|---|---|---|---|
| Cardiovascular disorders, hematological diseases, organismal injuries and abnormalities, and renal and urological disease | Renal vein thrombosis | Renal vein thrombosis | 0.0000364 | F10, SERPINC1 | 2 |
| Cellular movement and renal and urological system development and function | Migration | Migration of kidney cell lines | 0.000108 | C3, CHL1, F10, RBP3 | 4 |
| Cardiovascular disorders, cell death and survival, connective tissue disorders, hematological diseases, organismal injuries and abnormalities, and renal and urological disease | Atypical hemolytic uremic syndrome | Atypical hemolytic uremic syndrome | 0.000907 | C3, PLG | 2 |
| Organismal injuries and abnormalities and renal and urological disease | Failure | Failure of kidney | 0.00237 | C3, F10, SERPINC1, LCN2 | 4 |
| Developmental disorder, hereditary disorder, metabolic disease, organismal injuries and abnormalities, and renal and urological disease | Biotinidase deficiency | Biotinidase deficiency | 0.00249 | BTD | 1 |
| Organismal injuries and abnormalities and renal and urological disease | Septic acute kidney injury | Septic acute kidney injury | 0.00249 | LCN2 | 1 |
| Organismal injuries and abnormalities and renal and urological disease | Staghorn calculus | Staghorn calculus | 0.00249 | PLG | 1 |
| Cardiovascular disorders, cell death and survival, connective tissue disorders, hematological diseases, organismal injuries and abnormalities, and renal and urological disease | Susceptibility to atypical hemolytic uremic syndrome type 5 | Susceptibility to atypical hemolytic uremic syndrome type 5 | 0.00249 | C3 | 1 |
| Organismal injuries and abnormalities and renal and urological disease | End stage renal disease | End stage renal disease | 0.00318 | C3, F10, SERPINC1 | 3 |
| Cardiovascular diseases, cell death and survival, connective tissue disorders, hematological diseases, organismal injuries and abnormalities, and renal and urological disease | Atypical hemolytic uremic syndrome | Acute phase atypical hemolytic uremic syndrome | 0.00497 | C3 | 1 |
| Cell-to-cell signaling and interaction and renal and urological system development and function | Adhesion | Adhesion of kidney cell lines | 0.00664 | C3, F10 | 2 |
| Organismal injuries and abnormalities and renal and urological disease | Acute tubular necrosis | Acute tubular necrosis | 0.00745 | LCN2 | 1 |
| Organismal injuries and abnormalities and renal and urological disease | C3 glomerulopathy | C3 glomerulopathy | 0.00745 | C3 | 1 |
| Organismal injuries and abnormalities and renal and urological disease | Nephrosis | Nephrosis | 0.00861 | C3, F10, SERPINC1 | 3 |
| Immunological disease, inflammatory disease, inflammatory response, organismal injuries and abnormalities, andrenal and urological disease | Membranoproliferative glomerulonephritis | Membranoproliferative glomerulonephritis | 0.00992 | C3 | 1 |